Some targeted therapies work in a different way. These drugs target proteins that cause blood vessel growth. The goal is to “starve” the cancer by cutting off the blood supply that feeds it. Unlike other targeted therapies, these therapies do not need molecular testing.
The VEGF protein family causes blood vessel growth around cancers. Avastin targets VEGF-A. It can be taken in combination with chemotherapy. It can be given as a first treatment. It is given by vein. Mvasi is nearly the same therapy as Avastin. It is called a biosimilar.
Cyramza targets VEGFR2. It can be used after the cancer has grown during prior treatment. It is given together with chemotherapy. It is given by vein.